High Quality Content by WIKIPEDIA articles! Factor H is a member of the regulators of complement activation family and is a complement control protein. It is a large (155 kilodaltons), soluble glycoprotein that circulates in human plasma (at a concentration of 500–800 micrograms per milliliter). Its main job is to regulate the Alternative Pathway of the complement system, ensuring that the complement system is directed towards pathogens and does not damage host tissue. Factor H regulates...
High Quality Content by WIKIPEDIA articles! Factor H is a member of the regulators of complement activation family and is a complement control protein. It is a large (155 kilodaltons), soluble glycoprotein that circulates in human plasma (at a concentration of 500–800 micrograms per milliliter). Its main job is to regulate the Alternative Pathway of the complement system, ensuring that the complement system is directed towards pathogens and does not damage host tissue. Factor H regulates complement activation on self cells by possessing both cofactor activity for the Factor I mediated C3b cleavage, and decay accelerating activity against the alternative pathway C3 convertase, C3bBb. Factor H protects self cells from complement activation but not bacteria/viruses, in that it binds to glycosaminoglycans (GAGs) that are present on host cells but not pathogen cell surfaces.
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Маленький тролль по имени Сморчок — страшный ворчун и брюзга. Он всегда чем-то недоволен, и больше всего он хочет, чтобы его оставили в покое и не трогали. Но однажды случается нечто такое, что полностью меняет жизнь Сморчка. Может быть, он вовсе не такой уж неприветливый и грубый, каким кажется на первый взгляд? «Сморчок, маленький тролль» — замечательная история о преображающей силе дружбы. Даниэла...
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