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Characterization of Interleukin-33 and the IL-33 Receptor Complex. Cytokine Expression, Processing, Receptor Complex Formation and Signal Transduction

Код 913274

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Аннотация к книге "Characterization of Interleukin-33 and the IL-33 Receptor Complex. Cytokine Expression, Processing, Receptor Complex Formation and Signal Transduction"

Two pivotal aspects of the IL-33 system are characterized in this study: First the composition and function of the IL-33 receptor complex on IL-33 responder cells and second the generation of biologically active IL-33 by the IL-33 producer cell. IL-33 binds to the IL-33 receptor ?-chain (ST2) and as is shown here, this results in the recruitment of interleukin-1 receptor accessory protein (IL-1RAcP) as the co-receptor. The IL-33-dependent interaction of membrane bound and soluble form of...

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Издательство: Книга по требованию
Дата выхода: июль 2011
ISBN: 978-3-6391-4818-3
Объём: 136 страниц
Масса: 227 г
Размеры(высота, ширина, толщина), см: 23 x 16 x 1

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